Electrifying Technical Organic Syntheses
~the first major technology platform that drives the transfer of electroorganic syntheses from the laboratory to industrial scale~

Information material

Article about ETOS in industry magazine CHEManager (2026)

S. R. Waldvogel, S. Trosien, Elektrifizierung technischer organischer Synthesen
CHEManager 2/2026, p. 12. [CHEManager]


Review on scaling-up electro-organic chemistry 2026
D. F. Nater, P. Stenner, N. C. Aust, T. Gärtner, S. R. Waldvogel, Scaling-up electro-organic synthesis: challenges and
approaches
Current Opinion in Chemical Engineering 2026, 51, 101238. [DOI: 10.1016/j.coche.2026.101238]


Perspective article on electrochemical upcycling of persistent halogenated pollutants 2026 (see EVALINA)
S. B. Beil, S. R. Waldvogel, Upcycling of persistent pollutants: Toward an electrochemically driven circular halogen economy
Chem 2025, 12, 102831. [DOI: 10.1016/j.chempr.2025.102831]


Article about the renaissance of the electrosynthesis in the GIT Labor-Fachzeitschrift (2025)
M. S. Lenhard, J. Buchholz, S. R. Waldvogel, Renaissance der Elektrosynthese
GIT Labor-Fachzeitschrift 2025. [GIT Labor-Fachzeitschrift]


Overview article on the electrification of organic synthesis 2025
P. Röse, P. Neugebauer, S. Tamang, S. R. Waldvogel, U. Krewer, Trends and Challenges in Electrifying Technical Organic Synthesis
Chemie Ingenieur Technik 2025, 97, 395-410. [DOI: 10.1002/cite.202400155]


Overview article on the electrification of organic synthesis 2018

A. Wiebe, T. Gieshoff, S. Möhle, E. Rodrigo, M. Zirbes, S. R. Waldvogel, Electrifying Organic Synthesis
Angewandte Chemie International Edition 2018, 57, 5594–5619. [DOI: 10.1002/anie.201711060]
A. Wiebe, T. Gieshoff, S. Möhle, E. Rodrigo, M. Zirbes, S. R. Waldvogel, Elektrifizierung der organischen Synthese
Angewandte Chemie 2018, 130, 5694–5721. [DOI: 10.1002/ange.201711060]


Electrochemical arylation reactions

S. R. Waldvogel, S. Lips, M. Selt, B. Riehl, C. J. Kampf, Electrochemical Arylation Reactions
Chemical Reviews 2018, 118, 6706–6765. [DOI: 10.1021/acs.chemrev.8b00233]


Boron-doped diamond electrodes in electroorganic synthesis

S. Lips, S. R. Waldvogel, Use of Boron-doped Diamond Electrodes in Electro-organic Synthesis
ChemElectroChem 2019, 6, 1649–1660. [DOI: 10.1002/celc.201801620]


Dynamic methods for determining the state of electrodes

T. Vidaković-Koch, T. Miličić, L. A. Živković, H. S. Chan, U. Krewer, M. Petkovska, Nonlinear frequency response analysis: a recent review and perspectives
Current Opinion in Electrochemistry 2021, 30, 100851. [DOI: 10.1016/j.coelec.2021.100851]
F. Kubannek, U. Krewer, Studying the Interaction of Mass Transport and Electrochemical Reaction Kinetics by Species Frequency Response Analysis
Journal of The Electrochemical Society 2020, 167, 144510. [DOI: 10.1149/1945-7111/abc76e]


Electrode modeling

F. Kubannek, T. Turek, U. Krewer, Modeling Oxygen Gas Diffusion Electrodes for Various Technical Applications
Chemie Ingenieur Technik 2019, 91, 720–733. [DOI: 10.1002/cite.201800181]
M. Röhe, D. Franzen, F. Kubannek, B. Ellendorff, T. Turek, U. Krewer, Revealing the degree and impact of inhomogeneous electrolyte distributions on silver based gas diffusion electrodes
Electrochimica Acta 2021, 389, 138693. [DOI: 10.1016/j.electacta.2021.138693]
F. Röder, R. D. Braatz, U. Krewer, Direct coupling of continuum and kinetic Monte Carlo models for multiscale simulation of electrochemical systems
Computers & Chemical Engineering 2019, 121, 722-735. [DOI: 10.1016/j.compchemeng.2018.12.016]



Solvent control in electroorganic synthesis

L. Schulz, S. R. Waldvogel, Solvent Control in Electro-Organic Synthesis
Synlett 2019, 30, 275–286. [DOI: 10.1055/s-0037-1610303]


Description of multiphase transport

B. J. Etzold, U. Krewer, S. Thiele, A. Dreizler, E. Klemm, T. Turek, Understanding the activity transport nexus in water and CO2 electrolysis: State of the art, challenges, and perspectives
Chem. Eng. J. 2021, 424, 130501. [DOI: 10.1016/j.cej.2021.130501]


Model-based kinetics and degradation analysis

S. Triemer, M. Schulze, B. Wriedt, R. Schenkendorf, D. Ziegenbalg, U. Krewer, A. Seidel-Morgenstern, Kinetic analysis of the partial synthesis of artemisinin: Photooxygenation to the intermediate hydroperoxide
Journal of Flow Chemistry 2021, 11, 641-659. [DOI: 10.1007/s41981-021-00181-2]
J. Geppert, F. Kubannek, P. Röse, U. Krewer, Identifying the oxygen evolution mechanism by microkinetic modelling of cyclic voltammograms
Electrochimica Acta 2021, 380, 137902. [DOI: 10.1016/j.electacta.2021.137902]
T. Haisch, F. Kubannek, D. Chen, Y. Y. J. Tong, U. Krewer, Origin of the Drastic Current Decay during Potentiostatic Alkaline Methanol Oxidation
ACS Applied Materials & Interfaces 2020, 12, 43535–43542. [DOI: 10.1021/acsami.0c06547]


Modern aspects of electrochemistry for the synthesis of high-quality organic products

S. Möhle, M. Zirbes, E. Rodrigo, T. Gieshoff, A. Wiebe, S. R. Waldvogel, Modern Electrochemical Aspects for the Synthesis of Value-added Organic Products
Angewandte Chemie International Edition 2018, 57, 6018–6041. [DOI: 10.1002/anie.201712732]
S. Möhle, M. Zirbes, E. Rodrigo, T. Gieshoff, A. Wiebe, S. R. Waldvogel, Moderne Aspekte der Elektrochemie zur Synthese hochwertiger organischer Produkte
Angewandte Chemie 2018, 130, 6124–6149. [DOI: 10.1002/ange.201712732]


Myths and misunderstandings in electroorganic synthesis

S. B. Beil, D. Pollok, S. R. Waldvogel, Reproducibility in Electroorganic Synthesis – Myths and Misunderstandings
Angewandte Chemie International Edition 2021, 60, 14750–14759. [DOI: 10.1002/anie.202014544]
S. B. Beil, D. Pollok, S. R. Waldvogel, Reproduzierbarkeit in elektroorganischer Synthese – Mythen und Missverständnisse
Angewandte Chemie 2021, 133, 14874–14883. [DOI: 10.1002/ange.202014544]


Organic electrosynthesis - a technology of the 21st century

D. Pollok, S. R. Waldvogel, Electro-organic Synthesis – A 21st Century Technique
Chemical Science 2020, 11, 12375–12592. [DOI: 10.1039/D0SC01848A]


Reactor optimization

D. Witt, D. Wilde, F. Baakes, F. Belkhir, F. Röder, U. Krewer, Myth and Reality of a Universal Lithium-Ion Battery Electrode Design Optimum: A Perspective and Case Study
Energy Technology 2021, 9, 2000989. [DOI: 10.1002/ente.202000989]
X. Xie, R. Schenkendorf, U. Krewer, Toward a Comprehensive and Efficient Robust Optimization Framework for (Bio)chemical Processes

Processes 2018, 6, 183. [DOI: 10.3390/pr6100183]
V. N. Emenike, R. Schenkendorf, U. Krewer, A systematic reactor design approach for the synthesis of active pharmaceutical ingredients European Journal of Pharmaceutics and Biopharmaceutics 2018, 126, 75-88. [DOI: 10.1016/j.ejpb.2017.05.007]


Electrochemical transfer dihalogenation

X. Dong, J. L. Röckl, S. R. Waldvogel, B. Morandi, Merging shuttle reactions and paired electrolysis for reversible vicinal dihalogenations
Science 2021, 371, 507–514. [DOI: 10.1126/science.abf2974]